of 36. Sixteen foals had an
increase in SAA immediately
post plasma transfusion.
Assuming a blood volume
of 10% in each foal, the rise
in SAA immediately post
transfusion was similar to
the SAA value in the liter
of plasma. No reactions or
ill effects were noted in the
foals and neither SAA before
or after transfusion predicted
which foals might become
ill. Of the 9 foals who did not
show an increase in SAA post
plasma transfusion, none had
an SAA greater than 12 and
all received a lot of plasma
reserved for that farm. The SAA value in this batch of plasma was not measured.
The conclusion of this small trial should serve as a notice to practitioners to investigate the use of biologics in recent history when
interpreting increased SAA values. In addition to systemic inflammation and infection, the administration of exogenous SAA through
equine plasma products should be on your differential list.
REFERENCES
1. Nolen-Walston, Rose D.. "How to Interpret Serum Amyloid A Concentrations." (2015).
2. https://cdn.shopify.com/s/files/1/0190/5626/files/Neonatal_Screen_Protocol.pdf?7359911041967677412
EARLY
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